Graduate Student Researcher

  • Identified and characterized the molecular basis for noise in rod photoreceptors and its implications on the threshold of photon detection by leveraging genetic, electrophysiological and statistical tools.
  • Distinguished contributions of rod bipolar neurons to adaptation in the rod visual pathway, and identified the TRPM1-channel protein as a potential target for calcium that controls the boundary between rapid and prolonged adaptation to continuous light.
  • In addition to thesis work funded by T32 training grant (T32EY07026, 2018 – 2021), I collaborated with internal and external labs to UCLA where I contributed statistical and experimental work to the successful funding from 4 different NIH grants, 3 publications (Zhang et al. 2020, Reingruber et al. 2020, Griffis et al. 2022) and several conference abstracts (Griffis & Sampath 2021, Chung et al. 2022, for example).
  • Developed an open-source, MATLAB-based analysis framework and GUI, named Iris DVA, for transparent, documentable, and replicable analysis of physiological data.
  • Developed and supported custom hardware and software for precision control over light stimuli, for use in microspectrophotometry, electroretinography, and single-cell patch physiology rigs.

1 March 2016
  • Identified and characterized the molecular basis for noise in rod photoreceptors and its implications on the threshold of photon detection by leveraging genetic, electrophysiological and statistical tools.
  • Distinguished contributions of rod bipolar neurons to adaptation in the rod visual pathway, and identified the TRPM1-channel protein as a potential target for calcium that controls the boundary between rapid and prolonged adaptation to continuous light.
  • In addition to thesis work funded by T32 training grant (T32EY07026, 2018 – 2021), I collaborated with internal and external labs to UCLA where I contributed statistical and experimental work to the successful funding from 4 different NIH grants, 3 publications (Zhang et al. 2020, Reingruber et al. 2020, Griffis et al. 2022) and several conference abstracts (Griffis & Sampath 2021, Chung et al. 2022, for example).
  • Developed an open-source, MATLAB-based analysis framework and GUI, named Iris DVA, for transparent, documentable, and replicable analysis of physiological data.
  • Developed and supported custom hardware and software for precision control over light stimuli, for use in microspectrophotometry, electroretinography, and single-cell patch physiology rigs.

by:
Khris Griffis

https://khrisgriffis.com
Neurophysiology | Statistics | Biosignals Analysis | Data Science